Ms Hayley Floyd
MSc MSci (Hons)
Tracking and Evaluating the Influence of Metal Implant Wear Particles on Cellular Behaviour.
Metal alloys are commonly used in medical implants, and therefore there is great interest in the health effect of particulate wear debris. Biological responses investigated include the expression of inflammatory markers, which leads to aseptic loosening, the leading cause of revision surgery. The biological pathways leading to the expression of such proteins are unknown; however, they can be determined by performing live-cell confocal microscopy. This allows the cellular migration of wear particles to be tracked and their fate determined, and then correlated to known pathways. This project will investigate debris from both the articulating surface and precipitation of metal ions.
Hayley obtained her undergraduate master’s degree (MSci) in Physics from the University of Birmingham in 2012, during which time she completed two 10-week internships, in the Experimental Physics and the Medical Physics groups. She then went on to begin a PhD (with integrated study) at the Centre for Physical Sciences of Imaging in the Biomedical Sciences (PSIBS) Doctoral Training Centre, University of Birmingham.
Outside of the workplace Hayley enjoys boardgames, camping and art.